We strive to connect our community with studies and clinical trials in San Diego while they’re happening right now – find a few here that are actively enrolling participants. If you’re interested in how the actual trials are progressing and the general state of dementia research, sign up for our FREE annual research forum – Date with a Cure! It will be held virtually on June 10th, 2025, where you’ll be able to get your questioned answered by leading local researchers. Learn more about Date with a Cure >
Current Open Trials (as of April 2025)
Alzheimer’s Therapeutic Research Institute (Keck School of Medicine of USC)
Alzheimer Prevention Trials (APT) Webstudy: An online cognitive assessment research study aimed at accelerating the enrollment time for clinical trials designed to prevent Alzheimer’s disease. The purpose of the webstudy is to develop a large online group of individuals who may be at higher risk for developing Alzheimer’s dementia, and who may be interested in participating in a prevention trial.
For more information and additional USC trials, call 858-964-4644 or visit atri.usc.edu/studies/.
Sharp Neurocognitive Research Center
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline (TRAILRUNNER-ALZ3): Seeking participants who are between 65 and 80 years old and have mild or no memory problems. This clinical trial is investigating the efficacy of a drug in individuals who may be at risk of developing or worsening symptoms of Alzheimer’s disease. Learn more >
Advanced Brain Monitoring is looking for patients diagnosed with: Alzheimer’s, Parkinson’s, or Lewy Body Dementia, or Mild Cognitive Impairment 40-95 years old to participate in a computer-based study. Study participants will complete a series of computer-based memory and attention tasks. During this time, they will be recording brain activity using a cap with soft sensors. They are looking for patients with a definitive diagnosis of Alzheimer’s, Parkinson’s, or Lewy Body Dementia, or Mild Cognitive Impairment who feel comfortable sitting at a computer for 1-2 hours. The aim of the study is to help develop biomarkers that may be used by pharmaceutical companies in clinical trials to monitor the effectiveness of experimental drugs on neurodegenerative disease. The study visit(s) will last approximately 2-4 hours at their office in Carlsbad. Additionally, there will be a 2-night in-home sleep study. Participants will be compensated at a rate of $20 per hour upon study completion for every hour spent at the Advanced Brain Monitoring research facility as part of their participation in the study, and an additional $25 for completing the in-home sleep study.
To schedule a visit or request more information call: (760) 720-0099 ext. 6011 / Download flyer
The study “Validity of Functional Assessment Staging by Caregivers” put on by the Hahn School of Nursing at USD is looking for caregivers to help evaluate a mobile phone app about the stages of dementia. Contact: Shelby Bernauer (sbernauer@sandiego.edu / 858-630-1994). Learn more >
University of California – San Diego
TREAD study: What if the key to better brain health isn’t just what you eat but when you eat? Dr. Paula Desplats’ lab and the Alzheimer’s Disease Research Center at UCSD are exploring this question, which investigates how mealtimes affect Alzheimer’s disease symptoms. This study investigates whether prolonged nightly fasting (14 hours) is feasible for patients diagnosed with mild cognitive impairment or Alzheimer’s, and will evaluate outcome measures related to pathology, cognition, circadian regulation, sleep, and markers of inflammation and aging. TREAD lasts for 6 months and only requires three in-person visits. As part of the study, participants wear an ActiGraph, similar to a wristwatch, to collect data about physical activity and sleep for two weeks around the visit times. Additionally, the study offers a compensation of up to $225. If you are interested in learning more about the study, contact the TREAD team at TREAD@health.ucsd.edu or leave a message via phone at (858) 822-3182.
See more opportunities from our local partners and other organizations in the community.
For personalized dementia support, call us at 858.492.4400 to speak with one of our dementia experts who are here to help San Diego County residents and/or those caring for someone living in San Diego County (Spanish speakers available). Also check out our free education classes, social activities, caregiver support groups, & more.
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Posted on April 7th, 2025
